370 research outputs found
CDSD: Chinese Dysarthria Speech Database
We present the Chinese Dysarthria Speech Database (CDSD) as a valuable
resource for dysarthria research. This database comprises speech data from 24
participants with dysarthria. Among these participants, one recorded an
additional 10 hours of speech data, while each recorded one hour, resulting in
34 hours of speech material. To accommodate participants with varying cognitive
levels, our text pool primarily consists of content from the AISHELL-1 dataset
and speeches by primary and secondary school students. When participants read
these texts, they must use a mobile device or the ZOOM F8n multi-track field
recorder to record their speeches. In this paper, we elucidate the data
collection and annotation processes and present an approach for establishing a
baseline for dysarthric speech recognition. Furthermore, we conducted a
speaker-dependent dysarthric speech recognition experiment using an additional
10 hours of speech data from one of our participants. Our research findings
indicate that, through extensive data-driven model training, fine-tuning
limited quantities of specific individual data yields commendable results in
speaker-dependent dysarthric speech recognition. However, we observe
significant variations in recognition results among different dysarthric
speakers. These insights provide valuable reference points for
speaker-dependent dysarthric speech recognition.Comment: 9 pages, 3 figure
Unprecedented Centimeter-Long Carbon Nitride Needles: Synthesis, Characterization and Applications
This is the peer reviewed version of the following article: Barrio, J., Lin, L., Amo‐Ochoa, P., Tzadikov, J., Peng, G., Sun, J., ... & Shalom, M. (2018). Unprecedented Centimeter‐Long Carbon Nitride Needles: Synthesis, Characterization and Applications. Small, 14(21), 1800633, which has been published in final form at https://doi.org/10.1002/smll.201800633.
This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived VersionsFree standing centimeter-long 1D nanostructures are highly attractive for electronic and optoelectronic devices due to their unique photophysical and electrical properties. Here a simple, large-scale synthesis of centimeter-long 1D carbon nitride (CN) needles with tunable photophysical, electric, and catalytic properties is reported. Successful growth of ultralong needles is acquired by the utilization of 1D organic crystal precursors comprised of CN monomers as reactants. Upon calcination at high temperatures, the shape of the starting crystal is fully preserved while the CN composition and porosity, and optical and electrical properties can be easily tuned by tailoring the starting elements ratio and final calcination temperature. The facile manipulation and visualization of the CN needles endow their direct electrical measurements by placing them between two conductive probes. Moreover, the CN needles exhibit good photocatalytic activity for hydrogen production owing to their improved light harvesting properties, high surface area, and advantageous energy bands position. The new growth strategy developed here may open opportunities for a rational design of CN and other metal-free materials with controllable directionality and tunable photophysical and electronic properties, toward their utilization in (photo)electronic devices.The authors thank Dr. Alex Upcher and Dr. Einat Nativ-Roth for their assistance with electronic microscopy analysis. The authors thank also the financial support from the Spanish Ministerio de Economía y Competitividad (MAT2016-77608-C3-1-P). The authors thank Dr. Hod for fruitful discussio
Salt-Inducible Kinase 2: An Oncogenic Signal Transmitter and Potential Target for Cancer Therapy
Salt-inducible kinase (SIK), which belongs to the sucrose non-fermenting 1/AMP-activated protein kinase family, was first discovered in the adrenal cortex of a rat on a high-salt diet. As an isoform of the SIK family, SIK2 modulates various biological functions and acts as a signal transmitter in various pathways. Compared with that in adjacent normal tissues, the expression of SIK2 is significantly higher in multiple types of tumors, which indicates its pivotal effect in oncogenesis. Studies on SIK2 have recently underlined its role in several signaling pathways, including the PI3K-Akt-mTOR pathway, the Hippo-YAP pathway, the LKB1-HDAC axis, and the cAMP-PKA axis. Moreover, a few small-molecule SIK2 inhibitors have been found to be able to rescue the oncogenicity of SIK2 during tumor development and reverse its abnormal activation of downstream pathways. In this mini-review, we discuss the results of in vivo and in vitro studies regarding the SIK2 mechanism in different signaling pathways, particularly their regulation of cancer cells. This work may provide new ideas for targeting SIK2 as a novel therapeutic strategy in tumor therapy
TiEV: The Tongji Intelligent Electric Vehicle in the Intelligent Vehicle Future Challenge of China
TiEV is an autonomous driving platform implemented by Tongji University of
China. The vehicle is drive-by-wire and is fully powered by electricity. We
devised the software system of TiEV from scratch, which is capable of driving
the vehicle autonomously in urban paths as well as on fast express roads. We
describe our whole system, especially novel modules of probabilistic perception
fusion, incremental mapping, the 1st and the 2nd planning and the overall
safety concern. TiEV finished 2016 and 2017 Intelligent Vehicle Future
Challenge of China held at Changshu. We show our experiences on the development
of autonomous vehicles and future trends
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